Article
Genetic susceptibility, biomarker respones, and cancer.
Mutation research - 1 Nov 2003
Norppa Hannu
Abstract excerpt
A large number of studies have reported associations between polymorphisms of xenobiotic-metabolizing enzymes (XMEs) and various cancers. However, the carcinogenic exposures behind such findings have usually been unclear. Information on susceptibility to specific carcinogens could better be obtained by examining situations where the exposure and the endpoint studied are nearer in time, i.e., by studying...
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