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Article

Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease.

Human genetics - 1 Mar 2005

Zoodsma Margreet, Nolte Ilja M, Schipper Martin, Oosterom Elvira, van der Steege Gerrit, de Vries Elisabeth G E, te Meerman Gerard J, van der Zee Ate G J

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme regulating the metabolism of folate and methionine. The potential influence of MTHFR activity on DNA methylation and on the availability of uridylates and thymidylates for DNA synthesis and repair presents MTHFR as a candidate for being a cancer-predisposing gene. In the present study, we have examined a large study population to determine whether...

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Identifiers

PMID: 15635481
DOI: 10.1007/s00439-004-1233-4

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Methylenetetrahydrofolate reductase (MTHFR) and susceptibility for (pre)neoplastic cervical disease.PMID 15635481Read ↗

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