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Article

Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population.

Medical oncology (Northwood, London, England) - 1 May 2014

Tang Weifeng, Zhang Sheng, Qiu Hao, Wang Lixin, Sun Bin, Yin Jun, Gu Haiyong

Abstract excerpt

Esophageal cancer is the sixth most common cancer worldwide. Esophageal squamous cell carcinoma (ESCC) is a fatal malignancy associated with low 5-year survival rate. The aim of this study was to assess the association between methylenetetrahydrofolate reductase (MTHFR) tagging single nucleotide polymorphisms (SNPs) rs1801133 C>T, rs3753584 A>G, rs4845882 G>A, rs4846048 A>G and rs9651118 T>C genotypes and ESCC...

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Share to Asian People
Share to Biomarkers, Tumor
Share to Carcinoma, Squamous Cell
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Share to Follow-Up Studies
Share to Methylenetetrahydrofolate Reductase (NADPH2)

Source

Identifiers

PMID: 24687778
DOI: 10.1007/s12032-014-0915-6

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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