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Article

Mechanisms of the inhibitory effects of amyloid beta-protein on synaptic plasticity.

Experimental gerontology - 1 Jan 2000

Rowan Michael J, Klyubin Igor, Wang Qinwen, Anwyl Roger

Abstract excerpt

Alzheimer's disease can be considered a protein misfolding disease. In particular, inappropriate processing of a proteolytic fragment of amyloid precursor protein, amyloid beta-protein (Abeta), in early stages of Alzheimer's disease may lead to stabilization of small oligomers that are highly mobile and have a potential to be extremely toxic assemblies. Recently, the importance of such soluble species of Abeta in...

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Identifiers

PMID: 15582282
DOI: 10.1016/j.exger.2004.06.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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