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Article

Mesendoderm specification depends on the function of Pou2, the class V POU-type transcription factor, during zebrafish embryogenesis.

Development, growth & differentiation - 1 Sept 2012

Khan Alam, Nakamoto Andrew, Tai Miyako, Saito Shinji, Nakayama Yukiko, Kawamura Akinori, Takeda Hiroyuki, Yamasu Kyo

Abstract excerpt

Zebrafish pou2, encoding the class V POU transcription factor orthologous to mouse Oct-3/4, has been implicated in different aspects of development, such as dorsoventral patterning, endoderm formation, and brain regionalization, by analyzing pou2 mutant embryos. In the present study, we first conducted overexpression of pou2-modified genes by mRNA injection, and found that pou2 and its active form (vp-pou2)...

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Identifiers

PMID: 22913532
DOI: 10.1111/j.1440-169X.2012.01369.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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