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Article

New horizons for studying human hepatotropic infections

23 Feb 2010

Abstract excerpt

The liver serves as a target organ for several important pathogens, including hepatitis B and C viruses (HBV and HCV, respectively) and the human malaria parasites, all of which represent serious global health problems. Because these pathogens are restricted to human hepatocytes, research in small animals has been compromised by the frailty of the current mouse xenotransplantation models. In this issue of the...

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PMID: 20179350
DOI: 10.1172/jci42338

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