Article
Fine mapping of a region on chromosome 8p gives evidence for a QTL contributing to individual differences in an anxiety-related personality trait: TPQ harm avoidance.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005
Dina Christian, Nemanov Lubov, Gritsenko Inga, Rosolio Naama, Osher Yamima, Heresco-Levy Uri, Sariashvilli Emma, Bachner-Melman Rachel, Zohar Ada H, Benjamin Jonathan, Belmaker Robert H, Ebstein Richard P
Abstract excerpt
The chromosome 8p region is of interest in human behavioral genetics since it harbors a susceptibility region not only for schizophrenia but also for anxiety-related personality traits such as harm avoidance and neuroticism. Towards verifying our preliminary linkage finding of a QTL for TPQ harm avoidance at chromosome 8p, we have now genotyped altogether 24 micro-satellite markers in 377 families. Using three...
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