Article
A genome-wide quantitative trait locus (QTL) linkage scan of NEO personality factors in Latino families segregating bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2017
Lee Byung Dae, Gonzalez Suzanne, Villa Erika, Camarillo Cynthia, Rodriguez Marco, Yao Yin, Guo Wei, Flores Deborah, Jerez Alvaro, Raventos Henriette, Ontiveros Alfonso, Nicolini Humberto, Escamilla Michael
Abstract excerpt
Personality traits have been suggested as potential endophenotypes for Bipolar Disorder (BP), as they can be quantitatively measured and show correlations with BP. The present study utilized data from 2,745 individuals from 686 extended pedigrees originally ascertained for having multiplex cases of BP (963 cases of BPI or schizoaffective BP). Subjects were assessed with the NEO Personality Inventory, Revised (NEO...
Topics
- Bipolar Disorder
- Chromosomes, Human
- Genetic Linkage
- Genome-Wide Association Study
- Genotype
- Hispanic or Latino
- Humans
- Personality Inventory
