Article
Personality endophenotypes for bipolar affective disorder: a family-based genetic association analysis.
Genes, brain, and behavior - 1 Nov 2008
Savitz J, van der Merwe L, Ramesar R
Abstract excerpt
Genetic analyses of complex conditions such as bipolar disorder (BD) may be facilitated by the use of intermediate phenotypes. Various personality traits are overrepresented in people with BD and their unaffected relatives, and may constitute genetically transmitted risk factors or endophenotypes of the illness. In this study, we administered a battery of seven different personality questionnaires comprising 19...
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