Article
Hostility in adolescents and adults: a genome-wide association study of the Young Finns.
Translational psychiatry - 21 Jun 2011
Merjonen P, Keltikangas-Järvinen L, Jokela M, Seppälä I, Lyytikäinen L-P, Pulkki-Råback L, Kivimäki M, Elovainio M, Kettunen J, Ripatti S, Kähönen M, Viikari J, Palotie A, Peltonen L, Raitakari O T, Lehtimäki T
Abstract excerpt
Hostility is a multidimensional personality trait with changing expression over the life course. We performed a genome-wide association study (GWAS) of the components of hostility in a population-based sample of Finnish men and women for whom a total of 2.5 million single-nucleotide polymorphisms (SNPs) were available through direct or in silico genotyping. Hostility dimensions (anger, cynicism and paranoia) were...
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