Article
Genome scan for loci predisposing to anxiety disorders using a novel multivariate approach: strong evidence for a chromosome 4 risk locus.
American journal of human genetics - 1 Apr 2006
Kaabi Belhassen, Gelernter Joel, Woods Scott W, Goddard Andrew, Page Grier P, Elston Robert C
Abstract excerpt
We conducted a 10-centimorgan linkage autosomal genome scan in a set of 19 extended American pedigrees (219 subjects) ascertained through probands with panic disorder. Several anxiety disorders--including social phobia, agoraphobia, and simple phobia--in addition to panic disorder segregate in these families. In previous studies of this sample, linkage analyses were based separately on each of the individual...
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