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Article

Role of the Serotonin Transporter Promoter Polymorphism in Anxiety-Related Traits

1 Oct 1998

Abstract excerpt

BACKGROUND: The heritability of interindividual variation in anxiety and other aspects of personality establishes that variants of genes influence these traits. A functional polymorphism in the promoter of the human serotonin transporter gene (SLC6A4*C) was identified and found to be linked to an anxiety-related personality trait, Neuroticism. The polymorphism affects gene transcription and, ultimately, gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9783565
DOI: 10.1001/archpsyc.55.10.936

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