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Article

Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression.

Journal of cellular biochemistry - 1 Mar 2005

Taniura Hideo, Kobayashi Masakatsu, Yoshikawa Kazuaki

Abstract excerpt

Necdin is a growth suppressor expressed predominantly in postmitotic neurons. The necdin gene is involved in the etiology of the genomic imprinting-associated neurodevelopmental disorder Prader-Willi syndrome and belongs to the MAGE gene family. All the MAGE family proteins contain a large homology domain termed the MAGE homology domain (MHD). We here characterize the regions of necdin required for the...

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PMID: 15578580
DOI: 10.1002/jcb.20345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression.PMID 15578580Read ↗

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