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Article

Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment.

AIDS (London, England) - 19 Nov 2004

Schildgen Oliver, Schewe Carl Knud, Vogel Martin, Däumer Martin, Kaiser Rolf, Weitner Lutwin, Matz Bertfried, Rockstroh Jürgen Kurt

Abstract excerpt

Three HIV-infected patients with chronic hepatitis B (genotype A) were switched to adefovir therapy after unsuccessful lamivudine treatment. Surprisingly, adefovir therapy failed, although none of the virus isolates displayed mutations known to be associated with adefovir resistance (A181V, N236T). In two isolates we identified hepatitis B virus DNA polymerase mutation L217R, in one case we found multiple...

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Identifiers

PMID: 15577546
DOI: 10.1097/00002030-200411190-00014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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