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Article

A novel hepatitis B virus mutation with resistance to adefovir but not to tenofovir in an HIV-hepatitis B virus-co-infected patient.

AIDS (London, England) - 14 Nov 2006

Lacombe Karine, Ollivet Aurélie, Gozlan Joel, Durantel Sandra, Tran Nathalie, Girard Pierre-Marie, Zoulim Fabien

Abstract excerpt

A molecular virology analysis performed in an HIV-hepatitis B virus (HBV) co-infected patient showed the emergence of an unusual HBV polymerase gene mutation (rt A181T) under adefovir therapy, conferring resistance to adefovir but not to tenofovir, as proved by in-vitro phenotypic analysis. This observation suggests that careful monitoring of co-infected patients is required to diagnose HBV resistance to...

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PMID: 17086064
DOI: 10.1097/01.aids.0000252061.35422.84

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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