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Article

Increased genotype frequency of N-acetyltransferase 2 slow acetylation in patients with rheumatoid arthritis.

Clinical pharmacology and therapeutics - 1 Sept 2002

Pawlik Andrzej, Ostanek Lidia, Brzosko Iwona, Gawroska-Szklarz Barbara, Brzosko Marek, Dabrowska-Zamojcin Ewa

Abstract excerpt

OBJECTIVES: Acetylation polymorphism can alter therapeutic responses and toxicity to certain xenobiotics and may also be a factor that influences a patient's susceptibility to certain diseases. We investigated whether patients with rheumatoid arthritis (RA) differed from healthy individuals with regard to genotype of the polymorphic enzyme N-acetyltransferase 2 (NAT2). METHODS: NAT2 polymorphism was compared in...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Arthritis, Rheumatoid

Share to Arylamine N-Acetyltransferase

Share to Chi-Square Distribution

Share to Confidence Intervals

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 12235453
DOI: 10.1067/mcp.2002.126740

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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