Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.

Thorax - 1 Jul 2003

Minematsu N, Nakamura H, Iwata M, Tateno H, Nakajima T, Takahashi S, Fujishima S, Yamaguchi K

Abstract excerpt

BACKGROUND: Nicotine is responsible for smoking dependence and is mainly metabolised by CYP2A6. Several types of genetic polymorphism of CYP2A6 have been reported, but their relation to smoking habit and chronic obstructive pulmonary disease (COPD) phenotypes has not been fully clarified. METHODS: 203 current or ex-smokers (lifelong cigarette consumption (CC) >/=10 pack years) with subclinical and established...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryl Hydrocarbon Hydroxylases
Share to Cytochrome P-450 CYP2A6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Deletion

Share to Gene Frequency

Share to Mixed Function Oxygenases

Share to Pulmonary Emphysema

Share to Smoking

Share to Smoking Cessation

Source

Open in PubMed Open full text

Identifiers

PMID: 12832682
DOI: 10.1136/thorax.58.7.623
PMCID: PMC1746722

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CYP2A6 deletion polymorphism with smoking habit and development of pulmonary emphysema.PMID 12832682Read ↗

Association of CYP2A6 gene deletion with cigarette smoking status in Japanese adults.Semantic proximity Read ↗

Smoking behavior and related cancers: the role of CYP2A6 polymorphisms.Semantic proximity Read ↗

CYP2A6 deletion polymorphism is associated with decreased susceptibility of lung cancer in Asian smokers: a meta-analysis.Semantic proximity Read ↗

'Smoking genes': a genetic association study.Semantic proximity Read ↗

CYP2D6 gene polymorphism in caucasian smokers: lung cancer susceptibility and phenotype-genotype relationships.Semantic proximity Read ↗

Association of genetic polymorphisms CYP2A6*2 rs1801272 and CYP2A6*9 rs28399433 with tobacco-induced lung Cancer: case-control study in an Egyptian population.Semantic proximity Read ↗

Association of CYP2A6 gene polymorphisms with cigarette consumption: a meta-analysis.Semantic proximity Read ↗

Functional variants at CYP2A6: new genotyping methods, population genetics, and relevance to studies of tobacco dependence.Semantic proximity Read ↗

Smoking cessation program and CYP2A6 polymorphism.Semantic proximity Read ↗

Genetically decreased CYP2A6 and the risk of tobacco dependence: a prospective study of novice smokers.Semantic proximity Read ↗

CYP2D6 genotype and smoking behaviour in cigarette smokers.Semantic proximity Read ↗

CYP2D6 genotypes in cigarette smokers and non-tobacco users.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.