Article
Conserved glycine residues in the fusion peptide of the paramyxovirus fusion protein regulate activation of the native state.
Journal of virology - 1 Dec 2004
Russell Charles J, Jardetzky Theodore S, Lamb Robert A
Abstract excerpt
Hydrophobic fusion peptides (FPs) are the most highly conserved regions of class I viral fusion-mediating glycoproteins (vFGPs). FPs often contain conserved glycine residues thought to be critical for forming structures that destabilize target membranes. Unexpectedly, a mutation of glycine residu...
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