Article
Mutants of the paramyxovirus SV5 fusion protein: regulated and extensive syncytium formation.
Virology - 10 May 1995
Ward C D, Paterson R G, Lamb R A
Abstract excerpt
To study paramyxovirus-mediated cell fusion it would be advantageous to express in a cell a single protein that could cause regulated syncytium formation at neutral pH following a specific activation signal. We have constructed two SV5 fusion (F) protein mutants that contain three arginine residues in the cleavage site and two separate glycine to alanine changes in the fusion peptide. The mutants were expressed...
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