Article
Mutants of the paramyxovirus SV5 fusion protein: regulated and extensive syncytium formation.
Virology - 10 May 1995
Ward C D, Paterson R G, Lamb R A
Abstract excerpt
To study paramyxovirus-mediated cell fusion it would be advantageous to express in a cell a single protein that could cause regulated syncytium formation at neutral pH following a specific activation signal. We have constructed two SV5 fusion (F) protein mutants that contain three arginine residu...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Line
- Cytopathogenic Effect, Viral
- Genetic Vectors
- Molecular Sequence Data
- Mutation
- Respirovirus
- Simian virus 40
- Trypsin
- Viral Fusion Proteins