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Article

Genomewide linkage searches for Mendelian disease loci can be efficiently conducted using high-density SNP genotyping arrays.

Nucleic acids research - 23 Nov 2004

Sellick Gabrielle S, Longman Cheryl, Tolmie John, Newbury-Ecob Ruth, Geenhalgh Lynn, Hughes Simon, Whiteford Margo, Garrett Christine, Houlston Richard S

Abstract excerpt

Genomewide linkage searches aimed at identifying disease susceptibility loci are generally conducted using 300-400 microsatellite markers. Genotyping bi-allelic single nucleotide polymorphisms (SNPs) provides an alternative strategy. The availability of dense SNP maps coupled with recent technological developments in highly paralleled SNP genotyping makes it practical to now consider the use of these markers for...

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Identifiers

PMID: 15561999
DOI: 10.1093/nar/gnh163
PMCID: PMC534642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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