Article
Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.
Human genetics - 1 Dec 2009
McDonough Caitrin W, Bostrom Meredith A, Lu Lingyi, Hicks Pamela J, Langefeld Carl D, Divers Jasmin, Mychaleckyj Josyf C, Freedman Barry I, Bowden Donald W
Abstract excerpt
Genetic studies in Turkish, Native American, European American, and African American (AA) families have linked chromosome 18q21.1-23 to susceptibility for diabetes-associated nephropathy. In this study, we have carried out fine linkage mapping in the 18q region previously linked to diabetic nephropathy in AAs by genotyping both microsatellite and single nucleotide polymorphisms (SNPs) for linkage analysis in an...
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