Article
A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians.
Diabetes - 1 May 1999
Elbein S C, Hoffman M D, Teng K, Leppert M F, Hasstedt S J
Abstract excerpt
Considerable evidence supports a major inherited component of type 2 diabetes. We initially conducted a genome-wide scan with 440 microsatellite markers at 10-cM intervals in 19 multigenerational families of Northern European ancestry with at least two diabetic siblings. Initial two-point analyses of these families directed marker typing of 23 additional families. Subsequently, all available marker data on the...
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