Article
SNP HiTLink: a high-throughput linkage analysis system employing dense SNP data.
BMC bioinformatics - 24 Apr 2009
Fukuda Yoko, Nakahara Yasuo, Date Hidetoshi, Takahashi Yuji, Goto Jun, Miyashita Akinori, Kuwano Ryozo, Adachi Hiroki, Nakamura Eiji, Tsuji Shoji
Abstract excerpt
BACKGROUND: During this recent decade, microarray-based single nucleotide polymorphism (SNP) data are becoming more widely used as markers for linkage analysis in the identification of loci for disease-associated genes. Although microarray-based SNP analyses have markedly reduced genotyping time and cost compared with microsatellite-based analyses, applying these enormous data to linkage analysis programs is a...
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