Article
The maturation-dependent production of interleukin-16 is impaired in monocyte-derived dendritic cells from atopic dermatitis patients but is restored by inflammatory cytokines TNF-alpha and IL-1beta.
Experimental dermatology - 1 Dec 2004
Reich Kristian, Hugo Sabine, Middel Peter, Blaschke Volker, Heine Andrea, Neumann Christine
Abstract excerpt
BACKGROUND: Maturation of dendritic cells (DCs) influences important DC functions such as production of cytokines. Recently, DCs were identified as a source of interleukin-16 (IL-16), a chemotactic factor for DCs themselves, CD4+ T cells, and eosinophils. There is evidence that DC-derived IL-16 m...
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