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Article

Association of common polymorphisms in β1-adrenergic receptor with antihypertensive response to carvedilol.

Journal of cardiovascular pharmacology - 1 Oct 2014

Si Dayong, Wang Juan, Xu Ying, Chen Xiaoshuai, Zhang Mingqiu, Zhou Hui

Abstract excerpt

OBJECTIVES: Marked interpatient variability exists in the blood pressure response to carvedilol, a nonselective β-blocker. Here we evaluated the influence of 4 common polymorphisms in genes of the β-adrenergic receptor on the antihypertensive efficacy of carvedilol in patients in a double-blinded monotherapy study. METHODS: Eighty-seven subjects with uncomplicated essential hypertensive (49% men; age = 52.2 ±...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25291495
DOI: 10.1097/FJC.0000000000000119

Genes

ADRB1
ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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