Article
Preliminary study on association of beta2-adrenergic receptor polymorphism with hypertension in hypertensive subjects attending Balok Health Centre, Kuantan.
The Medical journal of Malaysia - 1 Feb 2012
Atia A E, Norsidah K, Nor Zamzila A, Rafidah Hanim M, Samsul D, Aznan M A M, Rashidah A R, Norlelawati A T
Abstract excerpt
Polymorphisms within the beta2-adrenergic receptor (ADRB2) gene have been repeatedly linked to hypertension. Among the ADRB2 polymorphisms detected, Arg16Gly and Gln27Glu codons are considered the two most important variations. The amino acid substitution at these codons may lead to abnormal regulation of ADRB2 activity. The aim of the present study was to assess the association between ADRB2 polymorphisms and...
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