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Article

Mycobacterial dissemination and cellular responses after 1-lobe restricted tuberculosis infection of genetically susceptible and resistant mice.

The Journal of infectious diseases - 15 Dec 2004

Mischenko Vladimir V, Kapina Marina A, Eruslanov Evgenyi B, Kondratieva Elena V, Lyadova Irina V, Young Douglas B, Apt Alexander S

Abstract excerpt

BACKGROUND AND METHODS: To study mycobacterial dissemination and immune-cell trafficking in tuberculosis, we developed a mouse model in which we introduced 1 microL of Mycobacterium tuberculosis directly into the middle lobe of the right lung. We investigated the kinetics of both mycobacterial spread to different anatomical sites and recruitment of phagocytes and activated lymphocytes. RESULTS: Mycobacterial...

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Identifiers

PMID: 15551212
DOI: 10.1086/425909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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