Article
Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism.
Biochemistry - 28 Feb 2012
Egli Martin, Mori Tetsuya, Pattanayek Rekha, Xu Yao, Qin Ximing, Johnson Carl H
Abstract excerpt
The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro from three proteins, KaiA, KaiB, and KaiC in the presence of ATP, to tick in a temperature-compensated manner. KaiC, the central cog of this oscillator, forms a homohexamer with 12 ATP molecules bound...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Bacterial Proteins
- CLOCK Proteins
- Catalytic Domain
- Circadian Rhythm Signaling Peptides and Proteins
- Crystallography, X-Ray
- Cyanobacteria
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Phosphorylation