Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.

PLoS computational biology - 1 Jan 2013

Hertel Stefanie, Brettschneider Christian, Axmann Ilka M

Abstract excerpt

Molecular genetic studies in the circadian model organism Synechococcus have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription. During 24 hours, KaiC hexamers run through different phospho-states during daytime. So far, it has remained unclear which phospho-state of KaiC promotes kaiBC expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Computer Simulation
Share to Cyanobacteria

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Models, Biological

Share to Mutation

Share to Phosphorylation

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23516349
DOI: 10.1371/journal.pcbi.1002966
PMCID: PMC3597532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.PMID 23516349Read ↗

Transcriptional autoregulation by phosphorylated and non-phosphorylated KaiC in cyanobacterial circadian rhythms.Semantic proximity Read ↗

No transcription-translation feedback in circadian rhythm of KaiC phosphorylation.Semantic proximity Read ↗

Global gene repression by KaiC as a master process of prokaryotic circadian system.Semantic proximity Read ↗

Circadian clocks go in vitro: purely post-translational oscillators in cyanobacteria.Semantic proximity Read ↗

Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro.Semantic proximity Read ↗

Phase-dependent generation and transmission of time information by the KaiABC circadian clock oscillator through SasA-KaiC interaction in cyanobacteria.Semantic proximity Read ↗

Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria.Semantic proximity Read ↗

Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock.Semantic proximity Read ↗

The recovery of KaiA's activity depends on its N-terminal domain and KaiB in the cyanobacterial circadian clock.Semantic proximity Read ↗

KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria.Semantic proximity Read ↗

Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution.Semantic proximity Read ↗

Circadian rhythms in the synthesis and degradation of a master clock protein KaiC in cyanobacteria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.