Article
Revealing a two-loop transcriptional feedback mechanism in the cyanobacterial circadian clock.
PLoS computational biology - 1 Jan 2013
Hertel Stefanie, Brettschneider Christian, Axmann Ilka M
Abstract excerpt
Molecular genetic studies in the circadian model organism Synechococcus have revealed that the KaiC protein, the central component of the circadian clock in cyanobacteria, is involved in activation and repression of its own gene transcription. During 24 hours, KaiC hexamers run through different...
Topics
- Bacterial Proteins
- Circadian Clocks
- Circadian Rhythm Signaling Peptides and Proteins
- Computational Biology
- Computer Simulation
- Cyanobacteria
- Feedback, Physiological
- Gene Expression Regulation, Bacterial
- Models, Biological
- Mutation
- Phosphorylation