Article
MEK partner 1 (MP1): regulation of oligomerization in MAP kinase signaling.
Journal of cellular biochemistry - 1 Mar 2005
Sharma Charu, Vomastek Tomás, Tarcsafalvi Adel, Catling Andrew D, Schaeffer Hans-Joerg, Eblen Scott T, Weber Michael J
Abstract excerpt
Specificity in signal transduction can be achieved through scaffolds, anchors, and adapters that assemble generic signal transduction components in specific combinations and locations. MEK Partner-1 (MP1) was identified as a potential "scaffold" protein for the mammalian extracellular signal-regulated kinase (ERK) pathway. To gain insight into the interactions of MP1 with the ERK pathway, we analyzed the ability...
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