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Article

Identification of B-KSR1, a novel brain-specific isoform of KSR1 that functions in neuronal signaling.

Molecular and cellular biology - 1 Aug 2000

Müller J, Cacace A M, Lyons W E, McGill C B, Morrison D K

Abstract excerpt

Kinase suppressor of Ras (KSR) is an evolutionarily conserved component of Ras-dependent signaling pathways. Here, we report the identification of B-KSR1, a novel splice variant of murine KSR1 that is highly expressed in brain-derived tissues. B-KSR1 protein is detectable in mouse brain throughout embryogenesis, is most abundant in adult forebrain neurons, and is complexed with activated mitogen-activated protein...

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Source

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Identifiers

PMID: 10891492
DOI: 10.1128/MCB.20.15.5529-5539.2000
PMCID: PMC86003

Genes

KSR1
EGF
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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