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Article

Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo.

Molecular and cellular biology - 1 May 2002

Nguyen AnhCo, Burack W Richard, Stock Jeffrey L, Kortum Robert, Chaika Oleg V, Afkarian Maryam, Muller William J, Murphy Kenneth M, Morrison Deborah K, Lewis Robert E, McNeish John, Shaw Andrey S

Abstract excerpt

While scaffold proteins are thought to be key components of signaling pathways, their exact function is unknown. By preassembling multiple components of signaling cascades, scaffolds are predicted to influence the efficiency and/or specificity of signaling events. Here we analyze a potential scaffold of the Ras/mitogen-activated protein kinase (MAPK) pathway, kinase suppressor of Ras (KSR), by generating...

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Identifiers

PMID: 11940661
DOI: 10.1128/MCB.22.9.3035-3045.2002
PMCID: PMC133772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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