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Article

The kinase activity of kinase suppressor of Ras1 (KSR1) is independent of bound MEK.

The Journal of biological chemistry - 18 Jun 2004

Xing H Rosie, Campodonico Luis, Kolesnick Richard

Abstract excerpt

Kinase Suppressor of Ras1 (KSR1) functions as a positive modulator of Ras-dependent signaling either upstream of or parallel to Raf-1, and pharmacologic inactivation of KSR1 may serve as a treatment for Rasdriven malignancies such as pancreatic cancer (Xing, H. R., Cordon-Cardo, C., Deng, X., Ton...

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Source

Identifiers

PMID: 15084597
DOI: 10.1074/jbc.M401323200

Genes

KSR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15084597-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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