Article
Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity.
Rheumatology (Oxford, England) - 1 Jan 2005
Jin L, Weisman M, Zhang G, Ward M, Luo J, Bruckel J, Inman R, Khan M A, Schumacher H R, Maksymowych W P, Mahowald M, Martin T, Rosenbaum J T, Yu D T Y, Stone M, Watson J, Dickman E, Davis J, Reveille J D
Abstract excerpt
OBJECTIVE: To study the linkage and association of ankylosing spondylitis (AS) with genotypes for matrix metalloproteinase 3 (MMP3), a gene located at chromosome 11q22.3 and lying within the 101-124 cM region observed in a recent genome-wide scan as a region associated with AS susceptibility. METHODS: MMP3 genotypes were examined in 229 pedigrees with AS, 131 sporadic AS cases and 87 Caucasian controls. Eight...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
