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Article

Mutational analysis of a site-specific recombinase: characterization of the catalytic and dimerization domains of the beta recombinase of pSM19035.

Molecular & general genetics : MGG - 1 Aug 1997

Canosa I, Ayora S, Rojo F, Alonso J C

Abstract excerpt

The beta recombinase encoded by the streptococcal plasmid pSM19035, which shows 28 to 34% identity with DNA resolvases and DNA invertases, can catalyze formation of deletions or inversions between properly oriented target sites. We have constructed a number of site-directed mutations at residues that are conserved between the beta protein and other DNA recombinases of the resolvase/invertase family. The analysis...

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PMID: 9294031
DOI: 10.1007/s004380050519

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