Article
Stage-specific repression by the EKLF transcriptional activator.
Molecular and cellular biology - 1 Dec 2004
Chen Xiaoyong, Bieker James J
Abstract excerpt
Dynamic changes in transcription factor function can be mediated by switching its interaction with coactivators and corepressors. Erythroid Kruppel-like factor (EKLF) is an erythroid cell-specific transcription factor that plays a critical role in beta-globin gene activation via its interactions with CBP/p300 and SWI/SNF proteins. Unexpectedly, it also interacts with Sin3A and histone deacetylase 1 (HDAC1)...
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