Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two kinds of ENU-induced scant hair mice and mapping of the mutant genes.

Journal of dermatological science - 1 Dec 2004

Wu Bao-Jin, Shao Yi-Xiang, Mao Hui-Hua, Tang Dong, Liu Jing, Xue Zheng-Feng, Li Hou-Da

Abstract excerpt

OBJECTIVE: To establish mouse models for human diseases through N-ethyl-N-nitrosourea (ENU) mutagenesis, and to provide groundwork to clone genes and study their functions after mapping the mutant genes. METHODS: 18 male D2 mice (G0) at age of 8-10 weeks old were injected intraperitoneally with ENU (100 mg/kg) once a week for three consecutive weeks. The treated male mice were mated with females of the same...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkylating Agents
Share to Ethylnitrosourea
Share to Genes, Dominant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Recessive

Share to Hair Diseases

Share to Mice, Inbred DBA

Share to Mice, Mutant Strains

Share to Mutagenesis

Source

Identifiers

PMID: 15541636
DOI: 10.1016/j.jdermsci.2004.08.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two kinds of ENU-induced scant hair mice and mapping of the mutant genes.PMID 15541636Read ↗

Now and future of mouse mutagenesis for human disease models.Semantic proximity Read ↗

Uncv (uncovered): a new mutation causing hairloss on mouse chromosome 11.Semantic proximity Read ↗

A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu.Semantic proximity Read ↗

Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice.Semantic proximity Read ↗

Dominant atopy risk mutations identified by mouse forward genetic analysis.Semantic proximity Read ↗

Nackt (nkt), a new hair loss mutation of the mouse with associated CD4 deficiency.Semantic proximity Read ↗

A new hairless mutant in the house mouse.Semantic proximity Read ↗

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.Semantic proximity Read ↗

ENU-induced mutant mice for a next-generation gene-targeting system.Semantic proximity Read ↗

Inherited mouse mutations: models for the study of alopecia.Semantic proximity Read ↗

Of hairless mice and men: the genetic basis of congenital alopecia universalis/congenital atrichia.Semantic proximity Read ↗

Four dominant autosomal mutations affecting skin and hair development in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.