Article
Of hairless mice and men: the genetic basis of congenital alopecia universalis/congenital atrichia.
Journal of cutaneous medicine and surgery - 1 Oct 1999
Bale S J
Abstract excerpt
BACKGROUND: Mouse models of human diseases help identify gene defects. OBJECTIVE: The methods of homozygosity mapping and mouse/human homology to identify genes are reviewed. The genotype/phenotype correlation in two clinical entities with mutations in the human hairless gene are discussed. METHODS: The example of the hairless mouse's contribution to our knowledge of hereditary alopecia is used, and the utility...
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