Article
Lack of association between Toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus.
Clinical and diagnostic laboratory immunology - 1 Nov 2004
Moore Catrin E, Segal Shelley, Berendt Anthony R, Hill Adrian V S, Day Nicholas P J
Abstract excerpt
To investigate a putative link between genetically determined variations in Toll-like receptor 2 (TLR2) and the occurrence of severe Staphylococcus aureus infection, the functional Arg753Gln single-nucleotide polymorphism and the GT repeat microsatellite in the TLR2 gene were examined in a large case-control study. No associations with disease or mortality attributable to these features were found.
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