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Article

Individual and combined effects of GSTM1, GSTT1, and GSTP1 polymorphisms on breast cancer risk: A meta-analysis and re-analysis of systematic meta-analyses.

PloS one - 1 Jan 2020

Miao Li-Feng, Ye Xiang-Hua, He Xiao-Feng

Abstract excerpt

BACKGROUND: Fourteen previous meta-analyses have been published to analyze the polymorphisms of individual GSTM1 present/null, GSTT1 present/null, and GSTP1 IIe105Val on breast cancer (BC) risk. However, their meta-analyses did not explore the combined effects of the three genetic polymorphisms on BC risk. In addition, they did not evaluate the credibility of statistically significant associations. Furthermore, a...

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PMID: 32155154
DOI: 10.1371/journal.pone.0216147
PMCID: PMC7064184

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