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Article

N1-substituent effects in the selective delivery of polyamine conjugates into cells containing active polyamine transporters.

Journal of medicinal chemistry - 18 Nov 2004

Gardner Richard Andrew, Delcros Jean-Guy, Konate Fanta, Breitbeil Fred, Martin Bénédicte, Sigman Michael, Huang Min, Phanstiel Otto

Abstract excerpt

Several N(1)-arylalkylpolyamines containing various aromatic ring systems were synthesized as their respective HCl salts. The N(1)-substituents evaluated ranged in size from N(1)-benzyl, N(1)-naphthalen-1-ylmethyl, N(1)-2-(naphthalen-1-yl)ethyl, N(1)-3-(naphthalen-1-yl)propyl, N(1)-anthracen-9-yl...

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Identifiers

PMID: 15537360
DOI: 10.1021/jm0497040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15537360-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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