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Article

Multidrug resistance modifies polyamines uptake in P388 murine lymphoma cells: experimental and modeling approach.

Biophysical chemistry - 29 Mar 1999

Berlaimont V, Bogaerts P, Dubois J, Hanus R, Hanocq M

Abstract excerpt

Polyamines (putrescine, spermidine and spermine) are ubiquitous compounds, essential for cell growth. This paper compares the polyamine transport between sensitive P388 murine lymphoma cells and two multidrug resistant P388 sublines with the assistance of an experimental model. This new model allows the characterisation of the whole polyamines uptake and efflux. Three parameters are identified by the model: two...

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PMID: 10326249
DOI: 10.1016/s0301-4622(99)00020-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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