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Article

Microsomal epoxide hydrolase, endotoxin, and lung function decline in cotton textile workers.

American journal of respiratory and critical care medicine - 15 Jan 2005

Hang Jingqing, Zhou Wei, Wang Xiaorong, Zhang Hongxi, Sun Bixiong, Dai Helian, Su Li, Christiani David C

Abstract excerpt

Occupational exposure to endotoxin in organic dust may induce lung function decline. Microsomal epoxide hydrolase (mEH) detoxifies reactive oxygen species generated by endotoxin exposure, and polymorphisms of the mEH gene are associated with altered enzyme activity. We investigated the associations between mEH polymorphisms, endotoxin exposure, and lung function decline in a 20-year prospective study of 265...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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PMID: 15531751
DOI: 10.1164/rccm.200407-888OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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