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Article

G protein polymorphisms do not predict weight loss and improvement of hypertension in severely obese patients.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Nov 2004

Potoczna Natascha, Wertli Maria, Steffen Rudolph, Ricklin Thomas, Lentes Klaus-Ulrich, Horber Fritz F

Abstract excerpt

Both the gene encoding the alpha subunit of G stimulatory proteins (GNAS1) and the beta3 subunit gene (GNB3) of G proteins are associated with obesity and/or hypertension. Moreover, the TT/TC825 polymorphism of GNB3 predicts greater weight loss than the CC825 polymorphism in obese patients (mean body mass index, 35 kg/m2) undergoing a structured nonpharmacologic weight loss program. Gastric banding enforces a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15531240
DOI: 10.1016/j.gassur.2004.08.004

Genes

GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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G protein polymorphisms do not predict weight loss and improvement of hypertension in severely obese patients.PMID 15531240Read ↗

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