Article
G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy.
Pharmacogenetics - 1 Apr 2003
Dishy Victor, Gupta Simi, Landau Ruth, Xie Hong-Guang, Kim Richard B, Smiley Richard M, Byrne Daniel W, Wood Alastair J J, Stein C Michael
Abstract excerpt
A common polymorphism (C825T) of the gene encoding the G-protein beta(3) subunit has been associated with obesity. We examined the hypothesis that this polymorphism affected weight gain during pregnancy. Two hundred and ninety-four women with uncomplicated term deliveries of singleton pregnancies were genotyped. Women homozygous for the T allele (TT) gained significantly more weight than women carrying the C...
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