Article
Diabetic ketoacidosis at diagnosis: role of family history and class II HLA genotypes.
European journal of endocrinology - 1 Jan 2013
Marigliano Marco, Morandi Anita, Maschio Maddalena, Costantini Silvia, Contreas Giovanna, D'Annunzio Giuseppe, Calcaterra Valeria, Maffeis Claudio
Abstract excerpt
OBJECTIVE: To explore the relationship between family history of diabetes and frequency of diabetic ketoacidosis (DKA) at diagnosis and to analyze the possible association between HLA genotypes and DKA. DESIGN AND METHODS: We recruited 510 children and adolescents aged <17 years with type 1 diabetes (T1D) and collected information on first-degree relative (FDR) history of T1D. DKA and severe DKA were defined as...
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