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Article

Trends in high-risk HLA susceptibility genes among Colorado youth with type 1 diabetes.

Diabetes care - 1 Jul 2008

Vehik Kendra, Hamman Richard F, Lezotte Dennis, Norris Jill M, Klingensmith Georgeanna J, Rewers Marian, Dabelea Dana

Abstract excerpt

OBJECTIVE: Type 1 diabetes is associated with a wide spectrum of susceptibility and protective genotypes within the HLA class II system. It has been reported that adults diagnosed with youth-onset type 1 diabetes more recently have been found to have fewer classical high-risk HLA class II genotypes than those diagnosed several decades ago. We hypothesized that such temporal trends in the distribution of HLA-DR,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Histocompatibility Antigens Class II

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Source

Open in PubMed Open full text

Identifiers

PMID: 18356404
DOI: 10.2337/dc07-2210
PMCID: PMC2453682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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