Article
Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden.
International journal of obesity (2005) - 1 May 2012
Carlsson A, Kockum I, Lindblad B, Engleson L, Nilsson A, Forsander G, Karlsson A-K, Kernell A, Ludvigsson J, Marcus C, Zachrisson I, Ivarsson S-A, Lernmark A
Abstract excerpt
OBJECTIVE: Type 1 diabetes and obesity has increased in childhood. We therefore tested the hypothesis that type 1 diabetes human leukocyte antigen DQ (HLA-DQ) risk genotypes may be associated with increased body mass index (BMI). DESIGN: The type 1 diabetes high-risk HLA-DQ A1*05:01-B1*02:01/A1*03:01-B1*03:02 genotype along with lower risk DQ genotypes were determined at the time of clinical onset by PCR and...
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