Article
p53 linear diffusion along DNA requires its C terminus.
Molecular cell - 5 Nov 2004
McKinney Kristine, Mattia Melissa, Gottifredi Vanesa, Prives Carol
Abstract excerpt
In cells, sequence-specific transcription factors must search through an entire genome to find their target sites in promoters. Such sites may be identified by using one-dimensional (linear diffusion) and/or three-dimensional (association/dissociation) mechanisms. We show here that wild-type p53...
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