A real-time PCR-based method to independently sample single simian immunodeficiency virus genomes from macaques with a range of viral loads.

Abstract excerpt

The generation of a diverse population of viral variants is a hallmark of simian immunodeficiency virus (SIV) infection. In order to address what role this diversity plays in disease progression, accurate sampling of the viral population is necessary. However, traditional PCR-based methods often rely on amplification of multiple genomes in one reaction, leading to resampling of viral genomes and potential errors...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA, Viral
• Share to Genome, Viral
• Share to Macaca nemestrina